Publications des scientifiques de l'IRD

Sosa-Estani S., Gamboa-Leon M. R., del Cid-Lemus J., Althahe F., Alger J., Almendares O., Cafferata M. L., Chippaux Jean-Philippe, Dumonteil E., Gibbons L., Padilla-Raygoza N., Schneider D., Belizan J. M., Buekens P. (2008). Short Report : Use of a rapid test on umbilical cord blood to screen for Trypanosoma cruzi infection in pregnant women in Argentina, Bolivia, Honduras, and Mexico. American Journal of Tropical Medicine and Hygiene, 79 (5), p. 755-759. ISSN 0002-9637.

Titre du document
Short Report : Use of a rapid test on umbilical cord blood to screen for Trypanosoma cruzi infection in pregnant women in Argentina, Bolivia, Honduras, and Mexico
Année de publication
2008
Type de document
Article
Auteurs
Sosa-Estani S., Gamboa-Leon M. R., del Cid-Lemus J., Althahe F., Alger J., Almendares O., Cafferata M. L., Chippaux Jean-Philippe, Dumonteil E., Gibbons L., Padilla-Raygoza N., Schneider D., Belizan J. M., Buekens P.
Source
American Journal of Tropical Medicine and Hygiene, 2008, 79 (5), p. 755-759 ISSN 0002-9637
We conducted a cross-sectional study of Chagas disease in five endemic areas in Argentina, Bolivia. Honduras, and Mexico to estimate the prevalence of Trypanosoma cruzi-specific antibodies in pregnant women, and to assess the use of a rapid test (Chagas Stat-Pak) to screen for T. cruzi infection ill the time of delivery. The prevalence of antibodies to T. cruzi measured by enzyme-linked immunosorbent assay (ELISA) in maternal blood was 5.5% (a range of 0.8-28.8% among the countries) in 2,495 women enrolled. Compared with ELISA in maternal blood samples, the Chagas Stat-Pak rapid test sensitivity and specificity in umbilical cord blood were 94.6% and 99.0%, respectively. These results show the ability for a rapid determination of the presence of T. cruzi-specific antibodies in umbilical cord blood as a pragmatic strategy to screen for infection in pregnant women.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052]
Localisation
Fonds IRD [F B010045376]
Identifiant IRD
fdi:010045376
Contact