Sosa-Estani S. auteur aut IRD Gamboa-Leon M. R. auteur aut IRD del Cid-Lemus J. auteur aut IRD Althahe F. auteur aut IRD Alger J. auteur aut IRD Almendares O. auteur aut IRD Cafferata M. L. auteur aut IRD Chippaux Jean-Philippe auteur aut IRD Dumonteil E. auteur aut IRD Gibbons L. auteur aut IRD Padilla-Raygoza N. auteur aut IRD Schneider D. auteur aut IRD Belizan J. M. auteur aut IRD Buekens P. auteur aut IRD text journalArticle eng text/pdf reformatted digital access We conducted a cross-sectional study of Chagas disease in five endemic areas in Argentina, Bolivia. Honduras, and Mexico to estimate the prevalence of Trypanosoma cruzi-specific antibodies in pregnant women, and to assess the use of a rapid test (Chagas Stat-Pak) to screen for T. cruzi infection ill the time of delivery. The prevalence of antibodies to T. cruzi measured by enzyme-linked immunosorbent assay (ELISA) in maternal blood was 5.5% (a range of 0.8-28.8% among the countries) in 2,495 women enrolled. Compared with ELISA in maternal blood samples, the Chagas Stat-Pak rapid test sensitivity and specificity in umbilical cord blood were 94.6% and 99.0%, respectively. These results show the ability for a rapid determination of the presence of T. cruzi-specific antibodies in umbilical cord blood as a pragmatic strategy to screen for infection in pregnant women. specialized 052 79 5 755-759 2008 0002-9637 https://www.documentation.ird.fr/hor/fdi:010045376 0002-9637 [F B010045376] https://www.documentation.ird.fr/hor/fdi:010045376 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers19-11/010045376.pdf IRD - Base Horizon / Pleins textes 2009-01-09 2019-12-16 fdi:010045376 fre