%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Sosa-Estani, S.
%A Gamboa-Leon, M. R.
%A del Cid-Lemus, J.
%A Althahe, F.
%A Alger, J.
%A Almendares, O.
%A Cafferata, M. L.
%A Chippaux, Jean-Philippe
%A Dumonteil, E.
%A Gibbons, L.
%A Padilla-Raygoza, N.
%A Schneider, D.
%A Belizan, J. M.
%A Buekens, P.
%T Short Report : Use of a rapid test on umbilical cord blood to screen for Trypanosoma cruzi infection in pregnant women in Argentina, Bolivia, Honduras, and Mexico
%D 2008
%L fdi:010045376
%G ENG
%J American Journal of Tropical Medicine and Hygiene
%@ 0002-9637
%M SP:000260945100025
%N 5
%P 755-759
%U https://www.documentation.ird.fr/hor/fdi:010045376
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers19-11/010045376.pdf
%V 79
%W Horizon (IRD)
%X We conducted a cross-sectional study of Chagas disease in five endemic areas in Argentina, Bolivia. Honduras, and Mexico to estimate the prevalence of Trypanosoma cruzi-specific antibodies in pregnant women, and to assess the use of a rapid test (Chagas Stat-Pak) to screen for T. cruzi infection ill the time of delivery. The prevalence of antibodies to T. cruzi measured by enzyme-linked immunosorbent assay (ELISA) in maternal blood was 5.5% (a range of 0.8-28.8% among the countries) in 2,495 women enrolled. Compared with ELISA in maternal blood samples, the Chagas Stat-Pak rapid test sensitivity and specificity in umbilical cord blood were 94.6% and 99.0%, respectively. These results show the ability for a rapid determination of the presence of T. cruzi-specific antibodies in umbilical cord blood as a pragmatic strategy to screen for infection in pregnant women.
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