Boulanger D., Schneider Dominique, Chippaux Jean-Philippe, Sellin Bertrand, Capron A. (1999). Schistosoma bovis : vaccine effects of a recombinant homologous glutathione S-transferase in sheep. International Journal for Parasitology, 29, p. 415-418. ISSN 0020-7519.
Titre du document
Schistosoma bovis : vaccine effects of a recombinant homologous glutathione S-transferase in sheep
Année de publication
1999
Type de document
Article
Auteurs
Boulanger D., Schneider Dominique, Chippaux Jean-Philippe, Sellin Bertrand, Capron A.
Source
International Journal for Parasitology, 1999,
29, p. 415-418 ISSN 0020-7519
The economic importance of the trematode Schistosoma bovis in African livestock has justified the development of a specific vaccine. Administered preventively to sheep, rSb28GST - the only molecule cloned from S. bovis which has demonstrated vaccine potentialities in goats and cattle - reduced the mean worm burden in vaccinated animals and improved their health status compared with that of non-vaccinated controls. As in goats, but not in bovines, the fecundity of the settled worm pairs was not modified. Therefore, rSb28GST can be proposed as a universal tool for the prevention of clinical disorders engendered by the main schistosome species affecting domestic ruminants in the African continent. (Résumé d'auteur)
