Schistosoma bovis : vaccine effects of a recombinant homologous glutathione S-transferase in sheep Boulanger, D. /Schneider, Dominique /Chippaux, Jean-Philippe /Sellin, Bertrand Capron, A. SCHISTOSOMIASE BETAIL VACCINATION ETUDE EXPERIMENTALE ETUDE COMPARATIVE GLUTATHIONE S TRANSFERASE The economic importance of the trematode Schistosoma bovis in African livestock has justified the development of a specific vaccine. Administered preventively to sheep, rSb28GST - the only molecule cloned from S. bovis which has demonstrated vaccine potentialities in goats and cattle - reduced the mean worm burden in vaccinated animals and improved their health status compared with that of non-vaccinated controls. As in goats, but not in bovines, the fecundity of the settled worm pairs was not modified. Therefore, rSb28GST can be proposed as a universal tool for the prevention of clinical disorders engendered by the main schistosome species affecting domestic ruminants in the African continent. (Résumé d'auteur) 1999 text https://www.documentation.ird.fr/hor/fdi:010026122 fdi:010026122 Boulanger D., Schneider Dominique, Chippaux Jean-Philippe, Sellin Bertrand, Capron A.. Schistosoma bovis : vaccine effects of a recombinant homologous glutathione S-transferase in sheep. 1999, 29, 415-418 EN AFRIQUE