Horizon 1 1 17 ACLN : Articles dans des revues avec comité de lecture non répertoriées par l'AERES International Journal for Parasitology 415-418 SCHISTOSOMIASE BETAIL VACCINATION ETUDE EXPERIMENTALE ETUDE COMPARATIVE GLUTATHIONE S TRANSFERASE AFRIQUE 1999 fdi:010026122 ENG International Journal for Parasitology 0020-7519 10.1016/S0020-7519(98)00222-7 https://www.documentation.ird.fr/hor/fdi:010026122 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_7/b_fdi_59-60/010026122.pdf 29 Horizon (IRD) The economic importance of the trematode #Schistosoma bovis$ in African livestock has justified the development of a specific vaccine. Administered preventively to sheep, rSb28GST - the only molecule cloned from #S. bovis$ which has demonstrated vaccine potentialities in goats and cattle - reduced the mean worm burden in vaccinated animals and improved their health status compared with that of non-vaccinated controls. As in goats, but not in bovines, the fecundity of the settled worm pairs was not modified. Therefore, rSb28GST can be proposed as a universal tool for the prevention of clinical disorders engendered by the main schistosome species affecting domestic ruminants in the African continent. (Résumé d'auteur) 052SCHIST03