%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture non répertoriées par l'AERES
%A Boulanger, D.
%A Schneider, Dominique
%A Chippaux, Jean-Philippe
%A Sellin, Bertrand
%A Capron, A.
%T Schistosoma bovis : vaccine effects of a recombinant homologous glutathione S-transferase in sheep
%D 1999
%L fdi:010026122
%G ENG
%J International Journal for Parasitology
%@ 0020-7519
%K SCHISTOSOMIASE ; BETAIL ; VACCINATION ; ETUDE EXPERIMENTALE ; ETUDE COMPARATIVE
%K GLUTATHIONE S TRANSFERASE
%K AFRIQUE
%P 415-418
%R 10.1016/S0020-7519(98)00222-7
%U https://www.documentation.ird.fr/hor/fdi:010026122
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_7/b_fdi_59-60/010026122.pdf
%V 29
%W Horizon (IRD)
%X The economic importance of the trematode #Schistosoma bovis$ in African livestock has justified the development of a specific vaccine. Administered preventively to sheep, rSb28GST - the only molecule cloned from #S. bovis$ which has demonstrated vaccine potentialities in goats and cattle - reduced the mean worm burden in vaccinated animals and improved their health status compared with that of non-vaccinated controls. As in goats, but not in bovines, the fecundity of the settled worm pairs was not modified. Therefore, rSb28GST can be proposed as a universal tool for the prevention of clinical disorders engendered by the main schistosome species affecting domestic ruminants in the African continent. (Résumé d'auteur)
%$ 052SCHIST03