Traore D. F., Sagna A. B., Assi S. B., Tchiekoi B. N., Adja A. M., Dagnogo M., Koffi A. A., Rogier C., Remoué Franck. (2021). Operational evaluation of the effectiveness of long-lasting insecticidal nets on human-vector contact in an African urban malaria context. Open Forum Infectious Diseases, 8 (2), p. ofaa635 [7 p.]. ISSN 2328-8957.
Titre du document
Operational evaluation of the effectiveness of long-lasting insecticidal nets on human-vector contact in an African urban malaria context
Traore D. F., Sagna A. B., Assi S. B., Tchiekoi B. N., Adja A. M., Dagnogo M., Koffi A. A., Rogier C., Remoué Franck
Source
Open Forum Infectious Diseases, 2021,
8 (2), p. ofaa635 [7 p.] ISSN 2328-8957
Background. Malaria is still a major public health concern in Cote d'Ivoire despite mass distribution of long-lasting insecticidal nets (LLINs) as a key preventive strategy. This study intended to evaluate the operational effectiveness of LLINs on the level of human-vector contact using 1 antibody-based biomarker of exposure to Anopheles in urban areas. Methods. This cross-sectional study collected socio-demographic data and use of LLINs from 9 neighborhoods in the city of Bouake (Cote d'Ivoire). Dry blood spots performed in children aged >6 months and adults were used to evaluate immunoglobulin G (IgG) responses to the Anopheles gSG6-P1 salivary peptide. Results. IgG response levels to the salivary peptide were significantly lower in individuals who declared having "always" (n=270) slept under an LLIN compared with those who had "often" (n=2087) and "never" (n=88) slept under an LLIN (P<.0001). IgG response levels to gSG6-P1 between those who declared having "always" and "not always" slept under an LLIN varied according to neighborhood, socio-professional category, and age group. Conclusions. The human IgG level to this gSG6-P1 salivary peptide could be a useful tool to evaluate the actual effectiveness of LLINs and help design behavioral change interventions that are crucial for sustaining universal coverage.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020]
;
Santé : généralités [050]
;
Entomologie médicale / Parasitologie / Virologie [052]
;
Urbanisation et sociétés urbaines [102]
