Prifti E., Zucker Jean-Daniel, Clément K., Henegar C. (2008). FunNet : an integrative tool for exploring transcriptional interactions. Bioinformatics, 24 (22), p. 2636-2638. ISSN 1367-4803.
Titre du document
FunNet : an integrative tool for exploring transcriptional interactions
Prifti E., Zucker Jean-Daniel, Clément K., Henegar C.
Source
Bioinformatics, 2008,
24 (22), p. 2636-2638 ISSN 1367-4803
We describe here an exploratory tool, called FunNet, which implements an original systems biology approach, aiming to improve the biological relevance of the modular interaction patterns identified in transcriptional co-expression networks. A suitable analytical model, involving two abstraction layers, has been devised to relate expression profiles to the knowledge on transcripts' biological roles, extracted from genomic databases, into a comprehensive exploratory framework. This approach has been implemented into a user-friendly web tool to promote its open use by the community.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020]
