Fontenille Didier, Diallo M., Mondo M., Ndiaye M., Thonnon J. (1997). First evidence of natural vertical transmission of yellow fever virus in Aedes aegypti, its epidemic vector. Transactions of the Royal Society of Tropical Medicine and Hygiene, 91 (5), p. 533-535. ISSN 0035-9203.
Titre du document
First evidence of natural vertical transmission of yellow fever virus in Aedes aegypti, its epidemic vector
Année de publication
1997
Auteurs
Fontenille Didier, Diallo M., Mondo M., Ndiaye M., Thonnon J.
Source
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1997,
91 (5), p. 533-535 ISSN 0035-9203
Entomological investigations were conducted in 1995 in Senegal, following a yellow fever (YF) outbreak. A total of 1125 mosquitoes collected in the field, including males, females and 12-48 h old newly emerged adults reared from wild-caught larvae, were tested for YF virus. Among the 22 species captured, Aedes aegypti was the most common. "Wild" vectors of YF were also captured, including A. furcifer, A. metallicus and A. luteocephalus. In all, 28 YF virus isolations were made : 19 from A. aegypti females, including 2 from newly emerged specimens, 2 from A. furcifer females, and one ech from a female A. metallicus and a female A. luteocephalus. The true infection rates (TIRs) were much higher in adult A. aegypti than in specimens reared from larvae-8.2% and 31.4% for female and male A. aegypti captured on human volunteers, respectively (P < 0.0001). The TIRs for A. aegypti reared from larvae were 1.4% and 0.5% for females and males, respectively (P > 0.05). This outbreak was an intermediate YF epidemic, involving 4 vector species. Our data provide the first evidence of vertical transmission of YF virus in nature by A. aegypti, its main vector to humans, and strongly suggest that vertical transmission played a major role in the spread of the epidemic. (Résumé d'auteur)
Plan de classement
Epidémiologie des arbovirus [052CULARB03]
Descripteurs
FIEVRE JAUNE ; EPIDEMIOLOGIE ; VECTEUR ; TRANSMISSION ; TRANSMISSION VERTICALE
Description Géographique
SENEGAL
Localisation
Fonds IRD [F B010011859] ;
Montpellier (Centre IRD)
Identifiant IRD
fdi:010011859
