@article{fdi:010011859, title = {{F}irst evidence of natural vertical transmission of yellow fever virus in {A}edes aegypti, its epidemic vector}, author = {{F}ontenille, {D}idier and {D}iallo, {M}. and {M}ondo, {M}. and {N}diaye, {M}. and {T}honnon, {J}.}, editor = {}, language = {{ENG}}, abstract = {{E}ntomological investigations were conducted in 1995 in {S}enegal, following a yellow fever ({YF}) outbreak. {A} total of 1125 mosquitoes collected in the field, including males, females and 12-48 h old newly emerged adults reared from wild-caught larvae, were tested for {YF} virus. {A}mong the 22 species captured, #{A}edes aegypti$ was the most common. "{W}ild" vectors of {YF} were also captured, including #{A}. furcifer$, #{A}. metallicus$ and #{A}. luteocephalus$. {I}n all, 28 {YF} virus isolations were made : 19 from #{A}. aegypti$ females, including 2 from newly emerged specimens, 2 from #{A}. furcifer$ females, and one ech from a female #{A}. metallicus$ and a female #{A}. luteocephalus$. {T}he true infection rates ({TIR}s) were much higher in adult #{A}. aegypti$ than in specimens reared from larvae-8.2% and 31.4% for female and male #{A}. aegypti$ captured on human volunteers, respectively ({P} < 0.0001). {T}he {TIR}s for #{A}. aegypti$ reared from larvae were 1.4% and 0.5% for females and males, respectively ({P} > 0.05). {T}his outbreak was an intermediate {YF} epidemic, involving 4 vector species. {O}ur data provide the first evidence of vertical transmission of {YF} virus in nature by #{A}. aegypti$, its main vector to humans, and strongly suggest that vertical transmission played a major role in the spread of the epidemic. ({R}{\'e}sum{\'e} d'auteur)}, keywords = {{FIEVRE} {JAUNE} ; {EPIDEMIOLOGIE} ; {VECTEUR} ; {TRANSMISSION} ; {TRANSMISSION} {VERTICALE} ; {SENEGAL}}, booktitle = {}, journal = {{T}ransactions of the {R}oyal {S}ociety of {T}ropical {M}edicine and {H}ygiene}, volume = {91}, numero = {5}, pages = {533--535}, ISSN = {0035-9203}, year = {1997}, DOI = {10.1016/{S}0035-9203(97)90013-4}, URL = {https://www.documentation.ird.fr/hor/fdi:010011859}, }