%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture non répertoriées par l'AERES
%A Fontenille, Didier
%A Diallo, M.
%A Mondo, M.
%A Ndiaye, M.
%A Thonnon, J.
%T First evidence of natural vertical transmission of yellow fever virus in Aedes aegypti, its epidemic vector
%D 1997
%L fdi:010011859
%G ENG
%J Transactions of the Royal Society of Tropical Medicine and Hygiene
%@ 0035-9203
%K FIEVRE JAUNE ; EPIDEMIOLOGIE ; VECTEUR ; TRANSMISSION
%K TRANSMISSION VERTICALE
%K SENEGAL
%N 5
%P 533-535
%R 10.1016/S0035-9203(97)90013-4
%U https://www.documentation.ird.fr/hor/fdi:010011859
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_6/b_fdi_47-48/010011859.pdf
%V 91
%W Horizon (IRD)
%X Entomological investigations were conducted in 1995 in Senegal, following a yellow fever (YF) outbreak. A total of 1125 mosquitoes collected in the field, including males, females and 12-48 h old newly emerged adults reared from wild-caught larvae, were tested for YF virus. Among the 22 species captured, #Aedes aegypti$ was the most common. "Wild" vectors of YF were also captured, including #A. furcifer$, #A. metallicus$ and #A. luteocephalus$. In all, 28 YF virus isolations were made : 19 from #A. aegypti$ females, including 2 from newly emerged specimens, 2 from #A. furcifer$ females, and one ech from a female #A. metallicus$ and a female #A. luteocephalus$. The true infection rates (TIRs) were much higher in adult #A. aegypti$ than in specimens reared from larvae-8.2% and 31.4% for female and male #A. aegypti$ captured on human volunteers, respectively (P < 0.0001). The TIRs for #A. aegypti$ reared from larvae were 1.4% and 0.5% for females and males, respectively (P > 0.05). This outbreak was an intermediate YF epidemic, involving 4 vector species. Our data provide the first evidence of vertical transmission of YF virus in nature by #A. aegypti$, its main vector to humans, and strongly suggest that vertical transmission played a major role in the spread of the epidemic. (Résumé d'auteur)
%$ 052CULARB03