Diouf F. S., Alou M. T., Bassene H., Cortaredona Sébastien, Diatta Georges, Raoult D., Sokhna Cheikh, Lagier J. C. (2024). Seasonal variation of asymptomatic viral and bacterial nasopharyngeal carriage in rural Senegal. Journal of Infection and Public Health, 17 (5), p. 922-928. ISSN 1876-0341.
Titre du document
Seasonal variation of asymptomatic viral and bacterial nasopharyngeal carriage in rural Senegal
Année de publication
2024
Auteurs
Diouf F. S., Alou M. T., Bassene H., Cortaredona Sébastien, Diatta Georges, Raoult D., Sokhna Cheikh, Lagier J. C.
Source
Journal of Infection and Public Health, 2024,
17 (5), p. 922-928 ISSN 1876-0341
Background: The surveillance of respiratory pathogens in rural areas of West Africa has, to date, largely been focussed on symptoms. In this prospective study conducted prior to the COVID-19 pandemic, we aimed to assess the asymptomatic prevalence of respiratory pathogen carriage in a group of individuals living in a rural area of Senegalese. Methods: Longitudinal follow up was performed through monthly nasopharyngeal swabbing during the dry season and weekly swabbing during the rainy season. We enrolled 15 individuals from the village of Ndiop. A total of 368 nasopharyngeal swabs were collected over a one-year period. We investigated the prevalence of 18 respiratory viruses and eight respiratory bacteria in different age groups using singleplex and multiplex PCR. Results: In total, 19.56% of the samples (72/368) were positive for respiratory viruses and 13.60% of the samples (50/368) were positive for respiratory bacteria. Coronaviruses (19/72, 26.39%), adenoviruses (17/72, 23.61%), rhinoviruses (14/72, 19.44%), Streptococcus pneumoniae (17/50, 34%), and Moraxella catarrhalis (15/ 50, 30%) were the most frequently detected viruses. Interestingly, the carriage of respiratory pathogens was shown to be more frequent during the rainy season, as pluviometry was shown to be positively associated with the occurrence of respiratory viruses such as influenza (P = .0078, r2 =.523) and RSV (P = .0055, r2 =.554). Conclusions: Our results show a non-negligible circulation of respiratory pathogens in a rural area in Senegal (West Africa) with an underestimated proportion of asymptomatic individuals. This study highlights the fact that the circulation of viruses and bacteria in the community has been overlooked.
Plan de classement
Santé : généralités [050]
;
Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
SENEGAL
Localisation
Fonds IRD [F B010090660]
Identifiant IRD
fdi:010090660
