@article{fdi:010090660,
  title = {{S}easonal variation of asymptomatic viral and bacterial nasopharyngeal carriage in rural {S}enegal},
  author = {{D}iouf, {F}. {S}. and {A}lou, {M}. {T}. and {B}assene, {H}. and {C}ortaredona, {S}{\'e}bastien and {D}iatta, {G}eorges and {R}aoult, {D}. and {S}okhna, {C}heikh and {L}agier, {J}. {C}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {T}he surveillance of respiratory pathogens in rural areas of {W}est {A}frica has, to date, largely been focussed on symptoms. {I}n this prospective study conducted prior to the {COVID}-19 pandemic, we aimed to assess the asymptomatic prevalence of respiratory pathogen carriage in a group of individuals living in a rural area of {S}enegalese. {M}ethods: {L}ongitudinal follow up was performed through monthly nasopharyngeal swabbing during the dry season and weekly swabbing during the rainy season. {W}e enrolled 15 individuals from the village of {N}diop. {A} total of 368 nasopharyngeal swabs were collected over a one-year period. {W}e investigated the prevalence of 18 respiratory viruses and eight respiratory bacteria in different age groups using singleplex and multiplex {PCR}. {R}esults: {I}n total, 19.56% of the samples (72/368) were positive for respiratory viruses and 13.60% of the samples (50/368) were positive for respiratory bacteria. {C}oronaviruses (19/72, 26.39%), adenoviruses (17/72, 23.61%), rhinoviruses (14/72, 19.44%), {S}treptococcus pneumoniae (17/50, 34%), and {M}oraxella catarrhalis (15/ 50, 30%) were the most frequently detected viruses. {I}nterestingly, the carriage of respiratory pathogens was shown to be more frequent during the rainy season, as pluviometry was shown to be positively associated with the occurrence of respiratory viruses such as influenza ({P} = .0078, r2 =.523) and {RSV} ({P} = .0055, r2 =.554). {C}onclusions: {O}ur results show a non-negligible circulation of respiratory pathogens in a rural area in {S}enegal ({W}est {A}frica) with an underestimated proportion of asymptomatic individuals. {T}his study highlights the fact that the circulation of viruses and bacteria in the community has been overlooked.},
  keywords = {{A}symptomatic ; {B}acteria ; {C}ohort ; {P}revalence ; {S}easonality ; {V}iruses ; {SENEGAL}},
  booktitle = {},
  journal = {{J}ournal of {I}nfection and {P}ublic {H}ealth},
  volume = {17},
  numero = {5},
  pages = {922--928},
  ISSN = {1876-0341},
  year = {2024},
  DOI = {10.1016/j.jiph.2024.03.020},
  URL = {https://www.documentation.ird.fr/hor/fdi:010090660},
}