Publications des scientifiques de l'IRD

Ferraris Pauline, Wichit S., Cordel N., Missé Dorothée. (2021). Human host genetics and susceptibility to ZIKV infection. Infection Genetics and Evolution, 95, 105066 [7 p.]. ISSN 1567-1348.

Titre du document
Human host genetics and susceptibility to ZIKV infection
Année de publication
2021
Type de document
Article référencé dans le Web of Science WOS:000696994700001
Auteurs
Ferraris Pauline, Wichit S., Cordel N., Missé Dorothée
Source
Infection Genetics and Evolution, 2021, 95, 105066 [7 p.] ISSN 1567-1348
Managing emerging infectious diseases is a current challenge in the fields of microbiology and epidemiology. Indeed, among other environmental and human-related factors, climate change and global warming favor the emergence of new pathogens. The recent Zika virus (ZIKV) epidemic, of which the large and rapid spread surprised the scientific community, is a reminder of the importance to study viruses currently responsible for sporadic infections. Increasing our knowledge of key factors involved in emerging infections is essential to implement specific monitoring that can be oriented according to the pathogen, targeted population, or at-risk environment. Recent technological developments, such as high-throughput sequencing, genome-wide association studies and CRISPR screenings have allowed the identification of human single nucleotide polymorphisms (SNPs) involved in infectious disease outcome. This review focuses on the human genetic host factors that have been identified and shown to be associated with the pathogenesis of ZIKV infection and candidate SNP targets.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020] ; Santé : généralités [050] ; Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
AFRIQUE ; ASIE ; AMERIQUE LATINE
Localisation
Fonds IRD [F B010083122]
Identifiant IRD
fdi:010083122
Contact