@article{fdi:010083122, title = {{H}uman host genetics and susceptibility to {ZIKV} infection}, author = {{F}erraris, {P}auline and {W}ichit, {S}. and {C}ordel, {N}. and {M}iss{\'e}, {D}oroth{\'e}e}, editor = {}, language = {{ENG}}, abstract = {{M}anaging emerging infectious diseases is a current challenge in the fields of microbiology and epidemiology. {I}ndeed, among other environmental and human-related factors, climate change and global warming favor the emergence of new pathogens. {T}he recent {Z}ika virus ({ZIKV}) epidemic, of which the large and rapid spread surprised the scientific community, is a reminder of the importance to study viruses currently responsible for sporadic infections. {I}ncreasing our knowledge of key factors involved in emerging infections is essential to implement specific monitoring that can be oriented according to the pathogen, targeted population, or at-risk environment. {R}ecent technological developments, such as high-throughput sequencing, genome-wide association studies and {CRISPR} screenings have allowed the identification of human single nucleotide polymorphisms ({SNP}s) involved in infectious disease outcome. {T}his review focuses on the human genetic host factors that have been identified and shown to be associated with the pathogenesis of {ZIKV} infection and candidate {SNP} targets.}, keywords = {{A}rbovirus ; {Z}ika virus ; {G}enetic factors ; {SNP} ; {AFRIQUE} ; {ASIE} ; {AMERIQUE} {LATINE}}, booktitle = {}, journal = {{I}nfection {G}enetics and {E}volution}, volume = {95}, numero = {}, pages = {105066 [7 ]}, ISSN = {1567-1348}, year = {2021}, DOI = {10.1016/j.meegid.2021.105066}, URL = {https://www.documentation.ird.fr/hor/fdi:010083122}, }