Agbota G., Fievet Nadine, Heude B., Accrombessi M., Ahouayito U., Yovo E., Dossa D., Dramane L., Gartner Agnès, Ezinmegnon S., Marcos J. Y., Vachot L., Tissieres P., Massougbodji A., Martin-Prével Yves, Cot Michel, Briand Valérie. (2019). Poor maternal anthropometric status before conception is associated with a deleterious infant growth during the first year of life : a longitudinal preconceptional cohort. Pediatric Obesity, 15 (1), e12573 [11 p.]. ISSN 2047-6310.
Titre du document
Poor maternal anthropometric status before conception is associated with a deleterious infant growth during the first year of life : a longitudinal preconceptional cohort
Année de publication
2019
Auteurs
Agbota G., Fievet Nadine, Heude B., Accrombessi M., Ahouayito U., Yovo E., Dossa D., Dramane L., Gartner Agnès, Ezinmegnon S., Marcos J. Y., Vachot L., Tissieres P., Massougbodji A., Martin-Prével Yves, Cot Michel, Briand Valérie
Source
Pediatric Obesity, 2019,
15 (1), e12573 [11 p.] ISSN 2047-6310
Background According to the Developmental Origins of Health and Diseases concept, exposures in the preconception period may be critical. For the first time, we evaluated the effect of preconception poor anthropometric status on infant's growth in sub-Saharan Africa. Methods A mother-child cohort was followed prospectively from preconception to 1 year old in Benin. Maternal anthropometric status was assessed by prepregnancy body mass index (BMI), approximated by BMI at the first antenatal visit before 7 weeks' gestation, and gestational weight gain (GWG). BMI was categorized as underweight, normal, overweight, and obesity according to World Health Organization standards. GWG was categorized as low (<7 kg), mild (7-12 kg), and high (>12 kg). In infant, stunting and wasting were defined as length-for-age and weight-for-length z scores less than -2 SD, respectively. We evaluated the association between BMI/GWG and infant's weight and length at birth and during the first year of life, as well as with stunting and wasting at 12 months using mixed linear and logistic regression models. Results In multivariate, preconceptional underweight was associated with a lower infant's weight at birth and during the first year (-164 g; 95% CI, -307 to -22; and -342 g; 95% CI, -624 to -61, respectively) and with a higher risk of stunting at 12 months (adjusted odds ratio [aOR] = 3.98; 95% CI, 1.01-15.85). Furthermore, preconceptional obesity and a high GWG were associated with a higher weight and length at birth and during the first year. Conclusion Underweight and obesity before conception as well as GWG were associated with infant's growth. These results argue for preventive interventions starting as early as the preconception period to support child long-term health.
Plan de classement
Santé : généralités [050]
;
Nutrition, alimentation [054]
Description Géographique
BENIN
Localisation
Fonds IRD [F B010077090]
Identifiant IRD
fdi:010077090
