Pallach M., Di Lorenzo F., Facchini F. A., Gully Djamel, Giraud Eric, Peri F., Duda K. A., Molinaro A., Silipo A. (2018). Structure and inflammatory activity of the LPS isolated from Acetobacter pasteurianus CIP103108. International Journal of Biological Macromolecules, 119, p. 1027-1035. ISSN 0141-8130.
Titre du document
Structure and inflammatory activity of the LPS isolated from Acetobacter pasteurianus CIP103108
Pallach M., Di Lorenzo F., Facchini F. A., Gully Djamel, Giraud Eric, Peri F., Duda K. A., Molinaro A., Silipo A.
Source
International Journal of Biological Macromolecules, 2018,
119, p. 1027-1035 ISSN 0141-8130
Acetobacter pasteurianus is an acetic add-producing Gram-negative bacterium commonly found associated with plants and plant products and widely used in the production of fermented foods, such as kefir and vinegar. Due to the acid conditions of the bacterium living habitat, uncommon structural features composing its cell envelope are expected. In the present work we have investigated the A. pasteurianus CIP103108 lipopolysaccharide (LPS) structure and immunoactivity. The structure of the lipid A and of two different O-polysaccharides was assessed. Furthermore, immunological studies with human cells showed a low immunostimulant activity of the isolated LPS, in addition to a slight capability to lower the NF-kappa B activation upon stimulation by toxic LPS.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020]
;
Santé : généralités [050]
;
Biotechnologies [084]
