@article{fdi:010074166, title = {{S}tructure and inflammatory activity of the {LPS} isolated from {A}cetobacter pasteurianus {CIP}103108}, author = {{P}allach, {M}. and {D}i {L}orenzo, {F}. and {F}acchini, {F}. {A}. and {G}ully, {D}jamel and {G}iraud, {E}ric and {P}eri, {F}. and {D}uda, {K}. {A}. and {M}olinaro, {A}. and {S}ilipo, {A}.}, editor = {}, language = {{ENG}}, abstract = {{A}cetobacter pasteurianus is an acetic add-producing {G}ram-negative bacterium commonly found associated with plants and plant products and widely used in the production of fermented foods, such as kefir and vinegar. {D}ue to the acid conditions of the bacterium living habitat, uncommon structural features composing its cell envelope are expected. {I}n the present work we have investigated the {A}. pasteurianus {CIP}103108 lipopolysaccharide ({LPS}) structure and immunoactivity. {T}he structure of the lipid {A} and of two different {O}-polysaccharides was assessed. {F}urthermore, immunological studies with human cells showed a low immunostimulant activity of the isolated {LPS}, in addition to a slight capability to lower the {NF}-kappa {B} activation upon stimulation by toxic {LPS}.}, keywords = {{L}ipopolysaccharides ({LPS}) ; {G}ram-negative bacteria ; {I}nnate immunity ; {MD}2-{TLR}4 ; {A}cetobacter pasteurianuss}, booktitle = {}, journal = {{I}nternational {J}ournal of {B}iological {M}acromolecules}, volume = {119}, numero = {}, pages = {1027--1035}, ISSN = {0141-8130}, year = {2018}, DOI = {10.1016/j.ijbiomac.2018.08.035}, URL = {https://www.documentation.ird.fr/hor/fdi:010074166}, }