Publications des scientifiques de l'IRD

Lemaitre M., Watier L., Briand Valérie, Garcia André, Le Hesran Jean-Yves, Cot Michel. (2014). Coinfection with Plasmodium falciparum and Schistosoma haematobium : additional evidence of the protective effect of Schistosomiasis on malaria in Senegalese children. American Journal of Tropical Medicine and Hygiene, 90 (2), p. 329-334. ISSN 0002-9637.

Titre du document
Coinfection with Plasmodium falciparum and Schistosoma haematobium : additional evidence of the protective effect of Schistosomiasis on malaria in Senegalese children
Année de publication
2014
Type de document
Article référencé dans le Web of Science WOS:000331009000028
Auteurs
Lemaitre M., Watier L., Briand Valérie, Garcia André, Le Hesran Jean-Yves, Cot Michel
Source
American Journal of Tropical Medicine and Hygiene, 2014, 90 (2), p. 329-334 ISSN 0002-9637
Parasitic infections are associated with high morbidity and mortality in developing countries. Several studies focused on the influence of helminth infections on malaria but the nature of the biological interaction is under debate. Our objective was to undertake a study to explore the influence of the measure of excreted egg load caused by Schistosoma haematobium on Plasmodium falciparum parasite densities. Ten measures of malaria parasite density and two measures of schistosomiasis egg urinary excretion over a 2-year follow-up period on 178 Senegalese children were considered. A linear mixed-effect model was developed to take data dependence into account. This work showed that children with a light S. haematobium infection (1-9 eggs/mL of urine) presented lower P. falciparum parasite densities than children not infected by S. haematobium (P < 0.04). Possible changes caused by parasite coinfections should be considered in the anti-helminth treatment of children and in malaria vaccination development.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
SENEGAL
Localisation
Fonds IRD [F B010061801]
Identifiant IRD
fdi:010061801
Contact