@article{fdi:010061801, title = {{C}oinfection with {P}lasmodium falciparum and {S}chistosoma haematobium : additional evidence of the protective effect of {S}chistosomiasis on malaria in {S}enegalese children}, author = {{L}emaitre, {M}. and {W}atier, {L}. and {B}riand, {V}al{\'e}rie and {G}arcia, {A}ndr{\'e} and {L}e {H}esran, {J}ean-{Y}ves and {C}ot, {M}ichel}, editor = {}, language = {{ENG}}, abstract = {{P}arasitic infections are associated with high morbidity and mortality in developing countries. {S}everal studies focused on the influence of helminth infections on malaria but the nature of the biological interaction is under debate. {O}ur objective was to undertake a study to explore the influence of the measure of excreted egg load caused by {S}chistosoma haematobium on {P}lasmodium falciparum parasite densities. {T}en measures of malaria parasite density and two measures of schistosomiasis egg urinary excretion over a 2-year follow-up period on 178 {S}enegalese children were considered. {A} linear mixed-effect model was developed to take data dependence into account. {T}his work showed that children with a light {S}. haematobium infection (1-9 eggs/m{L} of urine) presented lower {P}. falciparum parasite densities than children not infected by {S}. haematobium ({P} < 0.04). {P}ossible changes caused by parasite coinfections should be considered in the anti-helminth treatment of children and in malaria vaccination development.}, keywords = {{SENEGAL}}, booktitle = {}, journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene}, volume = {90}, numero = {2}, pages = {329--334}, ISSN = {0002-9637}, year = {2014}, DOI = {10.4269/ajtmh.12-0431}, URL = {https://www.documentation.ird.fr/hor/fdi:010061801}, }