Khamduang W., Jourdain Gonzague, Sirirungsi W., Layangool P., Kanjanavanit S., Krittigamas P., Pagdi K., Somsamai R., Sirinontakan S., Hinjiranandana T., Ardonk W., Hongsiriwon S., Nanta S., Borkird T., Lallemant Marc, McIntosh K., Ngo-Giang-Huong Nicole, Phpt Study Grp. (2011). The interrelated transmission of HIV-1 and cytomegalovirus during gestation and delivery in the offspring of HIV-infected mothers. Jaids.Journal of Acquired Immune Deficiency Syndromes, 58 (2), p. 188-192. ISSN 1525-4135.
Titre du document
The interrelated transmission of HIV-1 and cytomegalovirus during gestation and delivery in the offspring of HIV-infected mothers
Année de publication
2011
Auteurs
Khamduang W., Jourdain Gonzague, Sirirungsi W., Layangool P., Kanjanavanit S., Krittigamas P., Pagdi K., Somsamai R., Sirinontakan S., Hinjiranandana T., Ardonk W., Hongsiriwon S., Nanta S., Borkird T., Lallemant Marc, McIntosh K., Ngo-Giang-Huong Nicole, Phpt Study Grp
Source
Jaids.Journal of Acquired Immune Deficiency Syndromes, 2011,
58 (2), p. 188-192 ISSN 1525-4135
Our objective was to analyze, in formula-fed infants, correlates of HIV mother-to-child transmission, including cytomegalovirus (CMV) infection. HIV-infected infants were matched with HIV uninfected by maternal HIV RNA in a case-control design. Infant CMV infection was determined by CMV IgG at 18 months and timed by earlier CMV IgM or CMV DNA. Correlations were assessed using logistic regression. In utero HIV infection was independently associated with congenital CMV infection (P - 0.01), intrapartum HIV infection with congenital-plus-intrapartum/neonatal CMV infection (P = 0.01), and overall HIV with overall CMV infection (P = 0.001), and prematurity (P = 0.004). Congenital and acquired CMV infections are strong independent correlates of mother-to-child HIV transmission.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052]
Localisation
Fonds IRD [F B010053844]
Identifiant IRD
fdi:010053844
