Marin B., Boussinesq Michel, Druet Cabanac M., Kamgno J., Bouteille B., Preux P.M. (2006). Onchocerciasis-related epilepsy ? Prospects at a time of uncertainty. Trends in Parasitology, 22 (1), p. 17-20. ISSN 1471-4922.
Titre du document
Onchocerciasis-related epilepsy ? Prospects at a time of uncertainty
Trends in Parasitology, 2006,
22 (1), p. 17-20 ISSN 1471-4922
Epilepsy and onchocerciasis (river blindness) constitute serious public health problems in several tropical countries. There are four main mechanisms that might explain a relationship between these two diseases: (i) the presence of Onchocerca voivulus in the central nervous system; (ii) the pathogenicity of various O. volvulus strains; (iii) immunological mechanisms involving cross-reactive immunization or cytokine production during infection; and (iv) the triggering role of insomnia due to itching.
