%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Marin, B. %A Boussinesq, Michel %A Druet Cabanac, M. %A Kamgno, J. %A Bouteille, B. %A Preux, P.M. %T Onchocerciasis-related epilepsy ? Prospects at a time of uncertainty %D 2006 %L fdi:010051877 %G ENG %J Trends in Parasitology %@ 1471-4922 %M CC:0002349100-0006 %N 1 %P 17-20 %R 10.1016/j.pt.2005.11.006 %U https://www.documentation.ird.fr/hor/fdi:010051877 %> https://www.documentation.ird.fr/intranet/publi/depot/2011-06-01/010051877.pdf %V 22 %W Horizon (IRD) %X Epilepsy and onchocerciasis (river blindness) constitute serious public health problems in several tropical countries. There are four main mechanisms that might explain a relationship between these two diseases: (i) the presence of Onchocerca voivulus in the central nervous system; (ii) the pathogenicity of various O. volvulus strains; (iii) immunological mechanisms involving cross-reactive immunization or cytokine production during infection; and (iv) the triggering role of insomnia due to itching. %$ 052