Kouanfack C., Laborde-Balen G., Aghokeng Fobang Avelin, Bourgeois A., Dontsop M., Mben J. M., Kaze S., Mpoudi-Ngole E., Koulla-Shiro S., Delaporte Eric, Laurent Christian. (2010). WHO clinical criteria-based initiation of antiretroviral therapy : lessons from rural district hospitals in Cameroon with regard to 2009 revised WHO recommendations. Tropical Medicine and International Health, 15 (5), p. 580-583. ISSN 1360-2276.
Titre du document
WHO clinical criteria-based initiation of antiretroviral therapy : lessons from rural district hospitals in Cameroon with regard to 2009 revised WHO recommendations
Kouanfack C., Laborde-Balen G., Aghokeng Fobang Avelin, Bourgeois A., Dontsop M., Mben J. M., Kaze S., Mpoudi-Ngole E., Koulla-Shiro S., Delaporte Eric, Laurent Christian
Source
Tropical Medicine and International Health, 2010,
15 (5), p. 580-583 ISSN 1360-2276
P>Objective To assess the proportion of patients infected with HIV with a CD4 count above 350 cells/mm3 among those classified at WHO clinical stage 3 or 4 who initiated antiretroviral therapy in rural district hospitals in Cameroon to assess the 2009 revised WHO recommendations. Methods Cross-sectional study in nine rural district hospitals where the treatment initiation is based on the WHO clinical criteria. The proportion of patients who were classified at stage 3 or 4 and who had a CD4 count > 350 cells/mm3 was assessed. Results Of 458 patients included in 2006-2008 (women 70.5%; median age 37.0 years), 337 (73.6%) were classified at WHO clinical stage 3 and 121 (26.4%) at stage 4. Overall, 108 patients (23.6%) had a CD4 count > 350 cells/mm3. Of them, 94 patients (20.5%) were classified at WHO clinical stage 3, and 14 (3.1%) were classified at WHO clinical stage 4. Conclusion The WHO clinical stages 3 and 4 were poorly correlated with the 'gold standard' of CD4 cell count. This study highlights the need to promote CD4 testing for assessing the patient eligibility.
