%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Kouanfack, C.
%A Laborde-Balen, G.
%A Aghokeng Fobang, Avelin
%A Bourgeois, A.
%A Dontsop, M.
%A Mben, J. M.
%A Kaze, S.
%A Mpoudi-Ngole, E.
%A Koulla-Shiro, S.
%A Delaporte, Eric
%A Laurent, Christian
%T WHO clinical criteria-based initiation of antiretroviral therapy : lessons from rural district hospitals in Cameroon with regard to 2009 revised WHO recommendations
%D 2010
%L fdi:010049425
%G ENG
%J Tropical Medicine and International Health
%@ 1360-2276
%K Africa ; antiretroviral therapy ; HIV ; World Health Organization criteria
%M ISI:000276496100012
%N 5
%P 580-583
%R 10.1111/j.1365-3156.2010.02495.x
%U https://www.documentation.ird.fr/hor/fdi:010049425
%> https://www.documentation.ird.fr/intranet/publi/2010/04/010049425.pdf
%V 15
%W Horizon (IRD)
%X P>Objective To assess the proportion of patients infected with HIV with a CD4 count above 350 cells/mm3 among those classified at WHO clinical stage 3 or 4 who initiated antiretroviral therapy in rural district hospitals in Cameroon to assess the 2009 revised WHO recommendations. Methods Cross-sectional study in nine rural district hospitals where the treatment initiation is based on the WHO clinical criteria. The proportion of patients who were classified at stage 3 or 4 and who had a CD4 count > 350 cells/mm3 was assessed. Results Of 458 patients included in 2006-2008 (women 70.5%; median age 37.0 years), 337 (73.6%) were classified at WHO clinical stage 3 and 121 (26.4%) at stage 4. Overall, 108 patients (23.6%) had a CD4 count > 350 cells/mm3. Of them, 94 patients (20.5%) were classified at WHO clinical stage 3, and 14 (3.1%) were classified at WHO clinical stage 4. Conclusion The WHO clinical stages 3 and 4 were poorly correlated with the 'gold standard' of CD4 cell count. This study highlights the need to promote CD4 testing for assessing the patient eligibility.
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