Pinel Galzi Agnès, Mpunami A., Sangu E., Rakotomalala M., Traoré O., Sérémé D., Sorho F., Séré Y., Kanyeka Z., Konaté G., Fargette Denis. (2009). Recombination, selection and clock-like evolution of Rice yellow mottle virus. Virology, 394 (1), p. 164-172. ISSN 0042-6822.
Titre du document
Recombination, selection and clock-like evolution of Rice yellow mottle virus
Année de publication
2009
Auteurs
Pinel Galzi Agnès, Mpunami A., Sangu E., Rakotomalala M., Traoré O., Sérémé D., Sorho F., Séré Y., Kanyeka Z., Konaté G., Fargette Denis
Source
Virology, 2009,
394 (1), p. 164-172 ISSN 0042-6822
The clock-like diversification of Rice yellow mottle virus (RYMV), a widespread RNA plant virus that infects rice in Africa, was tested following a three-step approach with (i) an exhaustive search of recombinants, (ii) a comprehensive assessment of the selective constraints over lineages, and (iii) a stepwise series of tests of the molecular clock hypothesis. The first evidence of recombination in RYMV was found in East Africa, in the region most favorable to co-infection. RYMV evolved under a pronounced Purifying selection, but the selection pressure did vary among lineages. There was no phylogenetic evidence of transient deleterious mutations. ORF2b, which codes for the polymerase and is the most constrained ORF, tends to diversify clock-like. With the other ORFs and the full genome, the departure from the strict clock model was limited. This likely reflects the dominant conservative selection pressure and the clock-like fixation of synonymous mutations.
Plan de classement
Sciences du monde végétal [076]
Localisation
Fonds IRD [F B010048347]
Identifiant IRD
fdi:010048347
