@article{fdi:010048347, title = {{R}ecombination, selection and clock-like evolution of {R}ice yellow mottle virus}, author = {{P}inel {G}alzi, {A}gn{\`e}s and {M}punami, {A}. and {S}angu, {E}. and {R}akotomalala, {M}. and {T}raor{\'e}, {O}. and {S}{\'e}r{\'e}m{\'e}, {D}. and {S}orho, {F}. and {S}{\'e}r{\'e}, {Y}. and {K}anyeka, {Z}. and {K}onat{\'e}, {G}. and {F}argette, {D}enis}, editor = {}, language = {{ENG}}, abstract = {{T}he clock-like diversification of {R}ice yellow mottle virus ({RYMV}), a widespread {RNA} plant virus that infects rice in {A}frica, was tested following a three-step approach with (i) an exhaustive search of recombinants, (ii) a comprehensive assessment of the selective constraints over lineages, and (iii) a stepwise series of tests of the molecular clock hypothesis. {T}he first evidence of recombination in {RYMV} was found in {E}ast {A}frica, in the region most favorable to co-infection. {RYMV} evolved under a pronounced {P}urifying selection, but the selection pressure did vary among lineages. {T}here was no phylogenetic evidence of transient deleterious mutations. {ORF}2b, which codes for the polymerase and is the most constrained {ORF}, tends to diversify clock-like. {W}ith the other {ORF}s and the full genome, the departure from the strict clock model was limited. {T}his likely reflects the dominant conservative selection pressure and the clock-like fixation of synonymous mutations.}, keywords = {{M}olecular clock ; {R}ecombination ; {S}election pressure ; {P}hylogeography}, booktitle = {}, journal = {{V}irology}, volume = {394}, numero = {1}, pages = {164--172}, ISSN = {0042-6822}, year = {2009}, DOI = {10.1016/j.virol.2009.08.008}, URL = {https://www.documentation.ird.fr/hor/fdi:010048347}, }