Publications des scientifiques de l'IRD

Poinsignon Anne, Remoué Franck, Rossignol M., Cornélie Sylvie, Courtin David, Grébaut Pascal, Garcia André, Simondon François. (2008). Human IgG antibody response to glossina saliva : an epidemiologic marker of exposure to Glossina bites. American Journal of Tropical Medicine and Hygiene, 78 (5), p. 750-753. ISSN 0002-9637.

Titre du document
Human IgG antibody response to glossina saliva : an epidemiologic marker of exposure to Glossina bites
Année de publication
2008
Type de document
Article référencé dans le Web of Science WOS:000255568100015
Auteurs
Poinsignon Anne, Remoué Franck, Rossignol M., Cornélie Sylvie, Courtin David, Grébaut Pascal, Garcia André, Simondon François
Source
American Journal of Tropical Medicine and Hygiene, 2008, 78 (5), p. 750-753 ISSN 0002-9637
The evaluation of human antibody response specific to arthropod saliva may be a useful marker of exposure to vector-borne disease. Such an immunologic tool, applied to the evaluation of the exposure to Glossina bites, could be integrated in the control of human African trypanosomiasis (HAT). The antibody (IgG) response specific to uninfected Glossina fuscipes fuscipes saliva was evaluated according to the vector exposure and trypanic status in individuals residing in an HAT-endemic area. A high level of anti-saliva IgG antibodies was only detected in exposed individuals, whether infected or not by Trypanosoma brucei gambiense. In addition, the evaluation of specific IgG response represented spatial heterogeneity according to studied sites. These results suggest that the evaluation of anti-saliva IgG could be an indicator of Glossina exposure and thus could be integrated in other available tools to identify populations presenting risks of HAT transmission.
Plan de classement
Santé : généralités [050]
Localisation
Fonds IRD [F B010043749]
Identifiant IRD
fdi:010043749
Contact