@article{fdi:010043749, title = {{H}uman {I}g{G} antibody response to glossina saliva : an epidemiologic marker of exposure to {G}lossina bites}, author = {{P}oinsignon, {A}nne and {R}emou{\'e}, {F}ranck and {R}ossignol, {M}. and {C}orn{\'e}lie, {S}ylvie and {C}ourtin, {D}avid and {G}r{\'e}baut, {P}ascal and {G}arcia, {A}ndr{\'e} and {S}imondon, {F}ran{\c{c}}ois}, editor = {}, language = {{ENG}}, abstract = {{T}he evaluation of human antibody response specific to arthropod saliva may be a useful marker of exposure to vector-borne disease. {S}uch an immunologic tool, applied to the evaluation of the exposure to {G}lossina bites, could be integrated in the control of human {A}frican trypanosomiasis ({HAT}). {T}he antibody ({I}g{G}) response specific to uninfected {G}lossina fuscipes fuscipes saliva was evaluated according to the vector exposure and trypanic status in individuals residing in an {HAT}-endemic area. {A} high level of anti-saliva {I}g{G} antibodies was only detected in exposed individuals, whether infected or not by {T}rypanosoma brucei gambiense. {I}n addition, the evaluation of specific {I}g{G} response represented spatial heterogeneity according to studied sites. {T}hese results suggest that the evaluation of anti-saliva {I}g{G} could be an indicator of {G}lossina exposure and thus could be integrated in other available tools to identify populations presenting risks of {HAT} transmission.}, keywords = {}, booktitle = {}, journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene}, volume = {78}, numero = {5}, pages = {750--753}, ISSN = {0002-9637}, year = {2008}, URL = {https://www.documentation.ird.fr/hor/fdi:010043749}, }