Chandre Fabrice, Darriet Frédéric, Darder M., Cuany A., Doannio J.M.C., Pasteur N., Guillet Pierre. (1998). Pyrethroid resistance in Culex quinquefasciatus from West Africa. Medical and Veterinary Entomology, 12 (4), p. 359-366. ISSN 0269-283X.
Titre du document
Pyrethroid resistance in Culex quinquefasciatus from West Africa
Année de publication
1998
Type de document
Article
Auteurs
Chandre Fabrice, Darriet Frédéric, Darder M., Cuany A., Doannio J.M.C., Pasteur N., Guillet Pierre
Source
Medical and Veterinary Entomology, 1998,
12 (4), p. 359-366 ISSN 0269-283X
Pyrethroid resistance was investigated in thirty-three samples of Culex quinquefasciatus Say from twenty-five cities in Côte d'Ivoire and Burkina Faso. Permethrin resistance ratios at LC50 ranged from 9.5- to 82-fold in Côte d'Ivoire and from 17- to 49-fold in Burkina Faso. For deltamethrin, resistance ratios were lower and ranged from nine to thirty-eight in both countries. A strain was selected with permethrin to investigate resistance mechanisms. After forty-two generations of selection, permethrin resistance level reached 3750-fold, but deltamethrin resistance involved in permethrin resistance. Synergist assays and biochemical tests indicated that resistance was partly due to P450-dependent oxidases. A target site insensitivity (kdr) was also involved, associated with DDT cross resistance and a dramatic loss of permethrin knockdown effect on adults. This resistance should be taken into consideration when planning the use of pyrethroid-impregnated materials in urban area, as Culex is by far the main source of nuisance. Any failure in nuisance control due to resistance is likely to demotivate people in using impregnated materials. (Résumé d'auteur)
Plan de classement
Culicidés, arbovirus et maladies apparentées [052CULARB]
