%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture non répertoriées par l'AERES %A Chandre, Fabrice %A Darriet, Frédéric %A Darder, M. %A Cuany, A. %A Doannio, J.M.C. %A Pasteur, N. %A Guillet, Pierre %T Pyrethroid resistance in Culex quinquefasciatus from West Africa %D 1998 %L fdi:010015985 %G ENG %J Medical and Veterinary Entomology %@ 0269-283X %K FILARIOSE ; VECTEUR ; INSECTICIDE CHIMIQUE ; RESISTANCE ; LARVE ; ADULTE ; MORTALITE %K PERMETHRINE ; DELTAMETHRINE %K COTE D'IVOIRE ; BURKINA FASO %N 4 %P 359-366 %R 10.1046/j.1365-2915.1998.00120.x %U https://www.documentation.ird.fr/hor/fdi:010015985 %> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_7/b_fdi_51-52/010015985.pdf %V 12 %W Horizon (IRD) %X Pyrethroid resistance was investigated in thirty-three samples of #Culex quinquefasciatus$ Say from twenty-five cities in Côte d'Ivoire and Burkina Faso. Permethrin resistance ratios at LC50 ranged from 9.5- to 82-fold in Côte d'Ivoire and from 17- to 49-fold in Burkina Faso. For deltamethrin, resistance ratios were lower and ranged from nine to thirty-eight in both countries. A strain was selected with permethrin to investigate resistance mechanisms. After forty-two generations of selection, permethrin resistance level reached 3750-fold, but deltamethrin resistance involved in permethrin resistance. Synergist assays and biochemical tests indicated that resistance was partly due to P450-dependent oxidases. A target site insensitivity (kdr) was also involved, associated with DDT cross resistance and a dramatic loss of permethrin knockdown effect on adults. This resistance should be taken into consideration when planning the use of pyrethroid-impregnated materials in urban area, as #Culex$ is by far the main source of nuisance. Any failure in nuisance control due to resistance is likely to demotivate people in using impregnated materials. (Résumé d'auteur) %$ 052CULARB