Autran Daphné, Baroux C., Raissig M.T., Lenormand T., Wittig M., Grob S., Steimer A., Barann M., Klostermeier U.C., Leblanc Olivier, Vielle-Calzada J.P., Rosenstiel P., Grimanelli Daniel, Grossniklaus U. (2011). Maternal epigenetic pathways control parental contributions to Arabidopsis early embryogenesis. Cell, 145 (5), p. 707-719. ISSN 0092-8674.
Titre du document
Maternal epigenetic pathways control parental contributions to Arabidopsis early embryogenesis
Année de publication
2011
Auteurs
Autran Daphné, Baroux C., Raissig M.T., Lenormand T., Wittig M., Grob S., Steimer A., Barann M., Klostermeier U.C., Leblanc Olivier, Vielle-Calzada J.P., Rosenstiel P., Grimanelli Daniel, Grossniklaus U.
Source
Cell, 2011,
145 (5), p. 707-719 ISSN 0092-8674
Defining the contributions and interactions of paternal and maternal genomes during embryo development is critical to understand the fundamental processes involved in hybrid vigor, hybrid sterility, and reproductive isolation. To determine the parental contributions and their regulation during Arabidopsis embryogenesis, we combined deep-sequencing-based RNA profiling and genetic analyses. At the 2-4 cell stage there is a strong, genome-wide dominance of maternal transcripts, although transcripts are contributed by both parental genomes. At the globular stage the relative paternal contribution is higher, largely due to a gradual activation of the paternal genome. We identified two antagonistic maternal pathways that control these parental contributions. Paternal alleles are initially downregulated by the chromatin siRNA pathway, linked to DNA and histone methylation, whereas transcriptional activation requires maternal activity of the histone chaperone complex CAF1. Our results define maternal epigenetic pathways controlling the parental contributions in plant embryos, which are distinct from those regulating genomic imprinting.
Plan de classement
Sciences du monde végétal [076]
Identifiant IRD
PAR00007635
