Publications des scientifiques de l'IRD

Blinkova O., Victoria J., Li Y. Y., Keele B. F., Sanz C., Ndjango J. B. N., Peeters Martine, Travis D., Lonsdorf E. V., Wilson M. L., Pusey A. E., Hahn B. H., Delwart E. L. (2010). Novel circular DNA viruses in stool samples of wild-living chimpanzees. Journal of General Virology, 91 (Part 1), 74-86. ISSN 0022-1317.

Titre du document
Novel circular DNA viruses in stool samples of wild-living chimpanzees
Année de publication
2010
Type de document
Article référencé dans le Web of Science WOS:000273782200009
Auteurs
Blinkova O., Victoria J., Li Y. Y., Keele B. F., Sanz C., Ndjango J. B. N., Peeters Martine, Travis D., Lonsdorf E. V., Wilson M. L., Pusey A. E., Hahn B. H., Delwart E. L.
Source
Journal of General Virology, 2010, 91 (Part 1), 74-86 ISSN 0022-1317
Viral particles in stool samples from wild-living chimpanzees were analysed using random PCR amplification and sequencing. Sequences encoding proteins distantly related to the replicase protein of single-stranded circular DNA viruses were identified. Inverse PCR was used to amplify and sequence multiple small circular DNA viral genomes. The viral genomes were related in size and genome organization to vertebrate circoviruses and plant geminiviruses but with a different location for the stem-loop structure involved in rolling circle DNA replication. The replicase genes of these viruses were most closely related to those of the much smaller (similar to 1 kb) plant nanovirus circular DNA chromosomes. Because the viruses have characteristics of both animal and plant viruses, we named them chimpanzee stool-associated circular viruses (ChiSCV). Further metagenomic studies of animal samples will greatly increase our knowledge of viral diversity and evolution.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052] ; Sciences du monde animal [080]
Localisation
Fonds IRD [F B010089913]
Identifiant IRD
PAR00004650
Contact