@article{PAR00004650, title = {{N}ovel circular {DNA} viruses in stool samples of wild-living chimpanzees}, author = {{B}linkova, {O}. and {V}ictoria, {J}. and {L}i, {Y}. {Y}. and {K}eele, {B}. {F}. and {S}anz, {C}. and {N}django, {J}. {B}. {N}. and {P}eeters, {M}artine and {T}ravis, {D}. and {L}onsdorf, {E}. {V}. and {W}ilson, {M}. {L}. and {P}usey, {A}. {E}. and {H}ahn, {B}. {H}. and {D}elwart, {E}. {L}.}, editor = {}, language = {{ENG}}, abstract = {{V}iral particles in stool samples from wild-living chimpanzees were analysed using random {PCR} amplification and sequencing. {S}equences encoding proteins distantly related to the replicase protein of single-stranded circular {DNA} viruses were identified. {I}nverse {PCR} was used to amplify and sequence multiple small circular {DNA} viral genomes. {T}he viral genomes were related in size and genome organization to vertebrate circoviruses and plant geminiviruses but with a different location for the stem-loop structure involved in rolling circle {DNA} replication. {T}he replicase genes of these viruses were most closely related to those of the much smaller (similar to 1 kb) plant nanovirus circular {DNA} chromosomes. {B}ecause the viruses have characteristics of both animal and plant viruses, we named them chimpanzee stool-associated circular viruses ({C}hi{SCV}). {F}urther metagenomic studies of animal samples will greatly increase our knowledge of viral diversity and evolution.}, keywords = {}, booktitle = {}, journal = {{J}ournal of {G}eneral {V}irology}, volume = {91}, numero = {{P}art 1}, pages = {74--86}, ISSN = {0022-1317}, year = {2010}, DOI = {10.1099/vir.0.015446-0}, URL = {https://www.documentation.ird.fr/hor/{PAR}00004650}, }