Roux P., Fressard L., Suzan-Monti M., Chas J., Sagaon Teyssier Luis, Capitant C., Meyer L., Tremblay C., Rojas-Castro D., Pialoux G., Molina J. M., Spire B. (2018). Is on-demand HIV pre-exposure prophylaxis a suitable tool for men who have sex with men who practice chemsex ? Results from a substudy of the ANRS-IPERGAY trial. JAIDS. Journal of Acquired Immune Deficiency Syndromes, 79 (2), p. E69-E75. ISSN 1525-4135.
Titre du document
Is on-demand HIV pre-exposure prophylaxis a suitable tool for men who have sex with men who practice chemsex ? Results from a substudy of the ANRS-IPERGAY trial
Année de publication
2018
Auteurs
Roux P., Fressard L., Suzan-Monti M., Chas J., Sagaon Teyssier Luis, Capitant C., Meyer L., Tremblay C., Rojas-Castro D., Pialoux G., Molina J. M., Spire B.
Source
JAIDS. Journal of Acquired Immune Deficiency Syndromes, 2018,
79 (2), p. E69-E75 ISSN 1525-4135
Background: Chemsex-the use of psychoactive substances during sexual encounters-among men who have sex with men is a growing concern. On-demand HIV pre-exposure prophylaxis (PrEP) may be a suitable tool to prevent HIV transmission among "chemsexers." We used the open-label extension study of the ANRS-IPERGAY trial to describe chemsexers and their PrEP use. Methods: Among the 361 men who have sex with men enrolled in ANRS-IPERGAY's open-label extension study, we selected the 331 with available data on drug use. A 2-monthly web questionnaire on sociobehavioral data was used to compare sexual behaviors between questionnaires where chemsex was reported and those where it was not. Using a generalized estimating equation logistic regression, we studied whether practicing chemsex was associated with correct PrEP use. Results: Among the 331 participants, 30% reported chemsex practice at least once during follow-up and were considered chemsexers. Chemsex was reported in 16% of all questionnaires. Chemsexers were not significantly different from nonchemsexers regarding sociodemographic characteristics, although they reported greater use of anxiolytics and more sensation-seeking. Reporting chemsex was associated with more high-risk sexual practices and a higher perception of risk. After adjustment for other potential correlates, chemsex remained associated with correct PrEP use [odds ratio (95% confidence interval) = 2.24 (1.37 to 3.66)]. Conclusions: Our findings show that chemsexers were more likely to report high-risk sexual practices but also had a higher perception of risk. They were also more likely to use PrEP correctly when practicing chemsex. Consequently, PrEP may be a suitable tool to reduce HIV-risk transmission among chemsexers.
Plan de classement
Santé : généralités [050]
;
Entomologie médicale / Parasitologie / Virologie [052]
;
Santé : aspects socioculturels, économiques et politiques [056]
Description Géographique
FRANCE
Localisation
Fonds IRD [F B010074036]
Identifiant IRD
fdi:010074036
