@article{fdi:010074036, title = {{I}s on-demand {HIV} pre-exposure prophylaxis a suitable tool for men who have sex with men who practice chemsex ? {R}esults from a substudy of the {ANRS}-{IPERGAY} trial}, author = {{R}oux, {P}. and {F}ressard, {L}. and {S}uzan-{M}onti, {M}. and {C}has, {J}. and {S}agaon {T}eyssier, {L}uis and {C}apitant, {C}. and {M}eyer, {L}. and {T}remblay, {C}. and {R}ojas-{C}astro, {D}. and {P}ialoux, {G}. and {M}olina, {J}. {M}. and {S}pire, {B}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {C}hemsex-the use of psychoactive substances during sexual encounters-among men who have sex with men is a growing concern. {O}n-demand {HIV} pre-exposure prophylaxis ({P}r{EP}) may be a suitable tool to prevent {HIV} transmission among "chemsexers." {W}e used the open-label extension study of the {ANRS}-{IPERGAY} trial to describe chemsexers and their {P}r{EP} use. {M}ethods: {A}mong the 361 men who have sex with men enrolled in {ANRS}-{IPERGAY}'s open-label extension study, we selected the 331 with available data on drug use. {A} 2-monthly web questionnaire on sociobehavioral data was used to compare sexual behaviors between questionnaires where chemsex was reported and those where it was not. {U}sing a generalized estimating equation logistic regression, we studied whether practicing chemsex was associated with correct {P}r{EP} use. {R}esults: {A}mong the 331 participants, 30% reported chemsex practice at least once during follow-up and were considered chemsexers. {C}hemsex was reported in 16% of all questionnaires. {C}hemsexers were not significantly different from nonchemsexers regarding sociodemographic characteristics, although they reported greater use of anxiolytics and more sensation-seeking. {R}eporting chemsex was associated with more high-risk sexual practices and a higher perception of risk. {A}fter adjustment for other potential correlates, chemsex remained associated with correct {P}r{EP} use [odds ratio (95% confidence interval) = 2.24 (1.37 to 3.66)]. {C}onclusions: {O}ur findings show that chemsexers were more likely to report high-risk sexual practices but also had a higher perception of risk. {T}hey were also more likely to use {P}r{EP} correctly when practicing chemsex. {C}onsequently, {P}r{EP} may be a suitable tool to reduce {HIV}-risk transmission among chemsexers.}, keywords = {chemsex ; {P}r{EP} ; {HIV} ; harm reduction ; gay ; prevention ; {FRANCE}}, booktitle = {}, journal = {{JAIDS}. {J}ournal of {A}cquired {I}mmune {D}eficiency {S}yndromes}, volume = {79}, numero = {2}, pages = {{E}69--{E}75}, ISSN = {1525-4135}, year = {2018}, DOI = {10.1097/qai.0000000000001781}, URL = {https://www.documentation.ird.fr/hor/fdi:010074036}, }