%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Roux, P.
%A Fressard, L.
%A Suzan-Monti, M.
%A Chas, J.
%A Sagaon Teyssier, Luis
%A Capitant, C.
%A Meyer, L.
%A Tremblay, C.
%A Rojas-Castro, D.
%A Pialoux, G.
%A Molina, J. M.
%A Spire, B.
%T Is on-demand HIV pre-exposure prophylaxis a suitable tool for men who have sex with men who practice chemsex ? Results from a substudy of the ANRS-IPERGAY trial
%D 2018
%L fdi:010074036
%G ENG
%J JAIDS. Journal of Acquired Immune Deficiency Syndromes
%@ 1525-4135
%K chemsex ; PrEP ; HIV ; harm reduction ; gay ; prevention
%K FRANCE
%M ISI:000444643300003
%N 2
%P E69-E75
%R 10.1097/qai.0000000000001781
%U https://www.documentation.ird.fr/hor/fdi:010074036
%> https://www.documentation.ird.fr/intranet/publi/2018/09/010074036.pdf
%V 79
%W Horizon (IRD)
%X Background: Chemsex-the use of psychoactive substances during sexual encounters-among men who have sex with men is a growing concern. On-demand HIV pre-exposure prophylaxis (PrEP) may be a suitable tool to prevent HIV transmission among "chemsexers." We used the open-label extension study of the ANRS-IPERGAY trial to describe chemsexers and their PrEP use. Methods: Among the 361 men who have sex with men enrolled in ANRS-IPERGAY's open-label extension study, we selected the 331 with available data on drug use. A 2-monthly web questionnaire on sociobehavioral data was used to compare sexual behaviors between questionnaires where chemsex was reported and those where it was not. Using a generalized estimating equation logistic regression, we studied whether practicing chemsex was associated with correct PrEP use. Results: Among the 331 participants, 30% reported chemsex practice at least once during follow-up and were considered chemsexers. Chemsex was reported in 16% of all questionnaires. Chemsexers were not significantly different from nonchemsexers regarding sociodemographic characteristics, although they reported greater use of anxiolytics and more sensation-seeking. Reporting chemsex was associated with more high-risk sexual practices and a higher perception of risk. After adjustment for other potential correlates, chemsex remained associated with correct PrEP use [odds ratio (95% confidence interval) = 2.24 (1.37 to 3.66)]. Conclusions: Our findings show that chemsexers were more likely to report high-risk sexual practices but also had a higher perception of risk. They were also more likely to use PrEP correctly when practicing chemsex. Consequently, PrEP may be a suitable tool to reduce HIV-risk transmission among chemsexers.
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