Publications des scientifiques de l'IRD

Hernández-Andrade A., Moo-Millan J., Cigarroa-Toledo N., Ramos-Ligonio A., Herrera C., Bucheton Bruno, Bart Jean-Mathieu, Jamonneau Vincent, Banuls Anne-Laure, Paupy Christophe, Roiz David, Sereno Denis, Ibarra-Cerdena C.N., Machaín-Williams C., García-Rejón J., Gourbière S., Barnabé Christian, Telleria Jenny, Oury Bruno, Brenière F., Simard Frédéric, Rosado M., Solano Philippe, Dumonteil E., Waleckx Etienne. (2020). Metabarcoding : a powerful yet still underestimated approach for the comprehensive study of vector-borne pathogen transmission cycles and their dynamics. In : Claborn D. (ed.), Bhattacharya S. (ed.), Roy S. (ed.). Vector-borne diseases : recent developments in epidemiology and control. Londres : IntechOpen, 16 p. ISBN 978-1-83880-021-5.

Titre du document
Metabarcoding : a powerful yet still underestimated approach for the comprehensive study of vector-borne pathogen transmission cycles and their dynamics
Année de publication
2020
Type de document
Partie d'ouvrage
Auteurs
Hernández-Andrade A., Moo-Millan J., Cigarroa-Toledo N., Ramos-Ligonio A., Herrera C., Bucheton Bruno, Bart Jean-Mathieu, Jamonneau Vincent, Banuls Anne-Laure, Paupy Christophe, Roiz David, Sereno Denis, Ibarra-Cerdena C.N., Machaín-Williams C., García-Rejón J., Gourbière S., Barnabé Christian, Telleria Jenny, Oury Bruno, Brenière F., Simard Frédéric, Rosado M., Solano Philippe, Dumonteil E., Waleckx Etienne
In
Claborn D. (ed.), Bhattacharya S. (ed.), Roy S. (ed.), Vector-borne diseases : recent developments in epidemiology and control
Source
Londres : IntechOpen, 2020, 16 p. ISBN 978-1-83880-021-5
The implementation of sustainable control strategies aimed at disrupting the transmission of vector-borne pathogens requires a comprehensive knowledge of the vector ecology in the different eco-epidemiological contexts, as well as the local pathogen transmission cycles and their dynamics. However, even when focusing only on one specific vector-borne disease, achieving this knowledge is highly challenging, as the pathogen may exhibit a high genetic diversity and multiple vector species or subspecies and host species may be involved. In addition, the development of the pathogen and the vectorial capacity of the vectors may be affected by their midgut and/or salivary gland microbiome. The recent advent of Next-Generation Sequencing (NGS) technologies has brought powerful tools that can allow for the simultaneous identification of all these essential components, although their potential is only just starting to be realized. We present a metabarcoding approach that can facilitate the description of comprehensive host-pathogen networks, integrate important microbiome and coinfection data, identify at-risk situations, and disentangle the transmission cycles of vector-borne pathogens.This powerful approach should be generalized to unravel the transmission cycles of any pathogen and their dynamics, which in turn will help the design and implementation of sustainable, effective, and locally adapted control strategies.
Plan de classement
Santé : généralités [050] ; Entomologie médicale / Parasitologie / Virologie [052]
Localisation
Fonds IRD [F B010078825]
Identifiant IRD
fdi:010078825
Contact