Horizon / Plein textes La base de ressources documentaires de l'IRD

IRD

 

Publications des scientifiques de l'IRD

Zambrano M. R., Rouset F., Carrasco O. F., Murillo D. E., Costales J. A., Brenière Simone Frédérique. (2019). Congenital Chagas disease in the Ecuadorian Amazon : maternal screening at delivery and evaluation of risk factors associated with vector exposure. American Journal of Tropical Medicine and Hygiene, 101 (6), 1350-1358. ISSN 0002-9637

Accès réservé (Intranet IRD) Demander le PDF

Lien direct chez l'éditeur doi:10.4269/ajtmh.19-0340

Titre
Congenital Chagas disease in the Ecuadorian Amazon : maternal screening at delivery and evaluation of risk factors associated with vector exposure
Année de publication2019
Type de documentArticle référencé dans le Web of Science WOS:000500938900031
AuteursZambrano M. R., Rouset F., Carrasco O. F., Murillo D. E., Costales J. A., Brenière Simone Frédérique.
SourceAmerican Journal of Tropical Medicine and Hygiene, 2019, 101 (6), p. 1350-1358. ISSN 0002-9637
RésuméCongenital infection with Trypanosoma cruzi remains a major route for Chagas disease transmission in endemic and non-endemic regions. We evaluated an intervention strategy aimed to detect congenital Chagas disease cases at a major hospital in the Ecuadorian Amazon via cord blood analysis at the time of delivery. All women giving birth at the hospital during the study period (191) were invited to participate. Among them, two (1.0%) did not adjust to the inclusion criteria and four (2.1%) declined to participate in the study, showing the intervention had good acceptability among the mothers. It was possible to obtain cord blood samples during 146 of the deliveries, and only one woman was found to be seropositive, without evidence of transmission to the newborn at delivery or 8 months later. In addition, sociodemographic and economic characterization of the study population revealed that few women had previous knowledge about Chagas disease (16.1%) whereas more than half (62.5%) recognized the vector. Recognizing the vector and having seen it indoors were associated with women from rural families, involved in agriculture, and hunting in the forest. Interestingly, most women (87.3%) reported having easy access to Ecuador's national health system, suggesting serological screening during prenatal visits would be of value in this province. With a proper prenatal screening system in place, cord blood screening would allow for timely detection of T. cruzi infection in newborns from both seropositive women and the minority (2.1%) of women who do not comply with prenatal care visits.
Plan de classementEntomologie médicale / Parasitologie / Virologie [052] ; Santé : généralités [050]
Descr. géo.EQUATEUR ; AMAZONIE
LocalisationFonds IRD [F B010077425]
Identifiant IRDfdi:010077425
Lien permanenthttp://www.documentation.ird.fr/hor/fdi:010077425

Export des données

Disponibilité des documents

Télechargment fichier PDF téléchargeable

Lien sur le Web lien chez l'éditeur

Accès réservé en accès réservé

HAL en libre accès sur HAL


Accès aux documents originaux :

Le FDI est labellisé CollEx

Accès direct

Bureau du chercheur

Site de la documentation

Espace intranet IST (accès réservé)

Suivi des publications IRD (accès réservé)

Mentions légales

Services Horizon

Poser une question

Consulter l'aide en ligne

Déposer une publication (accès réservé)

S'abonner au flux RSS

Voir les tableaux chronologiques et thématiques

Centres de documentation

Bondy

Montpellier (centre IRD)

Montpellier (MSE)

Cayenne

Nouméa

Papeete

Abidjan

Dakar

Niamey

Ouagadougou

Tunis

La Paz

Quito