Augier C., Beyne Emmanuelle, Villabona-Arenas C. J., Ngole E. M., Peeters Martine, Ayouba Ahidjo. (2020). Identification of a novel simian immunodeficiency virus-infected African green monkey (Chlorocebus tantalus) confirms that Tantalus monkeys in Cameroon are infected with a mosaic SIVagm lineage. Aids Research and Human Retroviruses, 36 (2), 167-170. ISSN 0889-2229.
Titre du document
Identification of a novel simian immunodeficiency virus-infected African green monkey (Chlorocebus tantalus) confirms that Tantalus monkeys in Cameroon are infected with a mosaic SIVagm lineage
Augier C., Beyne Emmanuelle, Villabona-Arenas C. J., Ngole E. M., Peeters Martine, Ayouba Ahidjo
Source
Aids Research and Human Retroviruses, 2020,
36 (2), 167-170 ISSN 0889-2229
In this study we report on the identification of a simian immunodeficiency virus (SIV) infecting a Chlorocebus tantalus from Cameroon. The isolate, SIVagmTAN-CA1, was molecularly characterized by sequencing partial genome (similar to 4,000 bp) using the conventional Sanger method and the Oxford Nanopore Technology (ONT). In pol and gp41/nef SIVagmTAN-CA1 clusters with SIVagmSAB infecting Chlorocebus sabaeus from West Africa, whereas in env-gp120 it clusters with SIVagmTAN infecting C. tantalus from Central Africa. This mosaic structure is similar to that of a previously reported isolate infecting another tantalus monkey from Cameroon and confirms that the evolution of SIVagm is complex. Our data show that ONT sequencing gives results comparable with conventional Sanger sequencing on SIV and could help in distinguishing recombination and coinfection.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052]
;
Sciences du monde animal [080]
