Publications des scientifiques de l'IRD

Dicker D., Golan R., Aron-Wisnewsky J., Zucker Jean-Daniel, Sokolowska N., Comaneshter D. S., Yahalom R., Vinker S., Clement K., Rudich A. (2019). Prediction of long-term diabetes remission after rygb, sleeve gastrectomy, and adjustable gastric banding using DiaRem and Advanced-DiaRem scores. Obesity Surgery, 29 (3), p. 796-804. ISSN 0960-8923.

Titre du document
Prediction of long-term diabetes remission after rygb, sleeve gastrectomy, and adjustable gastric banding using DiaRem and Advanced-DiaRem scores
Année de publication
2019
Type de document
Article référencé dans le Web of Science WOS:000462182400007
Auteurs
Dicker D., Golan R., Aron-Wisnewsky J., Zucker Jean-Daniel, Sokolowska N., Comaneshter D. S., Yahalom R., Vinker S., Clement K., Rudich A.
Source
Obesity Surgery, 2019, 29 (3), p. 796-804 ISSN 0960-8923
Purpose DiaRem is a clinical scoring system designed to predict diabetes remission (DR) 1-year post-Roux-en-Y gastric bypass (RYGB). We examined long-term (2- and 5-year) postoperative DR prediction by DiaRem and an advanced-DiaRem (Ad-DiaRem) score following RYGB, sleeve gastrectomy (SG), and gastric banding (GB). Methods We accessed data from a computerized database of persons with type 2 diabetes and BMI >= 30 kg/m(2) who underwent RYGB, SG, or GB, and determined DR status 2- and 5-year postoperative according to preoperative DiaRem and the Ad-DiaRem calculated scores. Results Among 1459 patients with 5-year postoperative diabetes status data, 53.6% exhibited DR. For RYGB, Ad-DiaRem trended to exhibit mildly improved predictive capacity 5-year postoperatively compared to DiaRem: Areas under receiver operating characteristic [AUROC] curves were 0.85 (0.76-0.93) and 0.78 (0.69-0.88), respectively. The positive predictive values (PPVs) detecting >80% of those achieving DR (i.e., sensitivity >= 0.8) were 78.2% and 73.2%, respectively, and higher Ad-DiaRem scores more consistently associated with decreased DR rates. Following SG, both scores had an AUROC of 0.82, but Ad-DiaRem still had a higher PPV for predicting >80% of those with 5-year postoperative DR (76.2% and 71.0%). Predictive capacity parameters were comparatively lower, for both scores, when considering DR 5-year post-GB (AUROC: 0.73 for both scores, PPV: 66.3% and 64.3%, respectively). Conclusions Ad-DiaRem provides modest improvement compared to DiaRem in predicting long-term DR 5-years post-RYGB. Both scores similarly provide fair predictive capacity for 5-year postoperative DR after SG.
Plan de classement
Santé : généralités [050] ; Nutrition, alimentation [054]
Localisation
Fonds IRD [F B010075538]
Identifiant IRD
fdi:010075538
Contact