Combe Marine, Velvin C. J., Morris A., Garchitorena Andres, Carolan K., Sanhueza D., Roche Benjamin, Couppie P., Guégan Jean-François, Gozlan Rodolphe. (2017). Global and local environmental changes as drivers of Buruli ulcer emergence [+ erratum in Emerging Microbes and Infections.2017,6, e34]. Emerging Microbes and Infections - Nature, 6 (art. no e22), p. e22 [11 p.]. ISSN 2222-1751.
Titre du document
Global and local environmental changes as drivers of Buruli ulcer emergence [+ erratum in Emerging Microbes and Infections.2017,6, e34]
Année de publication
2017
Auteurs
Combe Marine, Velvin C. J., Morris A., Garchitorena Andres, Carolan K., Sanhueza D., Roche Benjamin, Couppie P., Guégan Jean-François, Gozlan Rodolphe
Source
Emerging Microbes and Infections - Nature, 2017,
6 (art. no e22), p. e22 [11 p.] ISSN 2222-1751
Many emerging infectious diseases are caused by generalist pathogens that infect and transmit via multiple host species with multiple dissemination routes, thus confounding the understanding of pathogen transmission pathways from wildlife reservoirs to humans. The emergence of these pathogens in human populations has frequently been associated with global changes, such as socio-economic, climate or biodiversity modifications, by allowing generalist pathogens to invade and persist in new ecological niches, infect new host species, and thus change the nature of transmission pathways. Using the case of Buruli ulcer disease, we review how land-use changes, climatic patterns and biodiversity alterations contribute to disease emergence in many parts of the world. Here we clearly show that Mycobacterium ulcerans is an environmental pathogen characterized by multi-host transmission dynamics and that its infectious pathways to humans rely on the local effects of global environmental changes. We show that the interplay between habitat changes (for example, deforestation and agricultural land-use changes) and climatic patterns (for example, rainfall events), applied in a local context, can lead to abiotic environmental changes and functional changes in local biodiversity that favor the pathogen's prevalence in the environment and may explain disease emergence.
Plan de classement
Sciences du milieu [021]
;
Ecologie, systèmes aquatiques [036]
;
Entomologie médicale / Parasitologie / Virologie [052]
;
Etudes, transformation, conservation du milieu naturel [082]
Description Géographique
ZONE TROPICALE
Localisation
Fonds IRD [F B010070024]
Identifiant IRD
fdi:010070024
