Melade J., McCulloch S., Ramasindrazana B., Lagadec E., Turpin M., Pascalis H., Goodman S. M., Markotter W., Dellagi Koussay. (2016). Serological evidence of Lyssaviruses among bats on Southwestern Indian Ocean islands. Plos One, 11 (8), p. e0160553 [13 p.]. ISSN 1932-6203.
Titre du document
Serological evidence of Lyssaviruses among bats on Southwestern Indian Ocean islands
We provide serological evidence of lyssavirus circulation among bats on southwestern Indian Ocean (SWIO) islands. A total of 572 bats belonging to 22 species were collected on Anjouan, Mayotte, La Reunion, Mauritius, Mahe and Madagascar and screened by the Rapid Fluorescent Focus Inhibition Test for the presence of neutralising antibodies against the two main rabies related lyssaviruses circulating on the African continent: Duvenhage lyssavirus (DUVV) and Lagos bat lyssavirus (LBV), representing phylogroups I and II, respectively. A total of 97 and 42 sera were able to neutralise DUVV and LBV, respectively. No serum neutralised both DUVV and LBV but most DUVV-seropositive bats (n = 32/220) also neutralised European bat lyssavirus 1 (EBLV-1) but not Rabies lyssavirus (RABV), the prototypic lyssavirus of phylogroup I. These results highlight that lyssaviruses belonging to phylogroups I and II circulate in regional bat populations and that the putative phylogroup I lyssavirus is antigenically closer to DUVV and EBLV-1 than to RABV. Variation between bat species, roost sites and bioclimatic regions were observed. All brain samples tested by RTPCR specific for lyssavirus RNA were negative.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052]
;
Sciences du monde animal [080]
Description Géographique
ANJOUAN ; MAYOTTE ; REUNION ; MAURICE ; MADAGASCAR
