Publications des scientifiques de l'IRD

Bahar O., Pruitt R., Luu D. D., Schwessinger B., Daudi A., Liu F., Ruan R., Fontaine-Bodin L., Koebnik Ralf, Ronald P. (2014). The Xanthomonas Ax21 protein is processed by the general secretory system and is secreted in association with outer membrane vesicles. Peerj, 2, p. e242 [14 p.]. ISSN 2167-8359.

Titre du document
The Xanthomonas Ax21 protein is processed by the general secretory system and is secreted in association with outer membrane vesicles
Année de publication
2014
Type de document
Article référencé dans le Web of Science WOS:000347555200001
Auteurs
Bahar O., Pruitt R., Luu D. D., Schwessinger B., Daudi A., Liu F., Ruan R., Fontaine-Bodin L., Koebnik Ralf, Ronald P.
Source
Peerj, 2014, 2, p. e242 [14 p.] ISSN 2167-8359
Pattern recognition receptors (PRRs) play an important role in detecting invading pathogens and mounting a robust defense response to restrict infection. In rice, one of the best characterized PRRs is XA21, a leucine rich repeat receptor-like kinase that confers broad-spectrum resistance to multiple strains of the bacterial pathogen Xanthomonas oryzae pv. oryzae (Xoo). In 2009 we reported that an Xoo protein, called Ax21, is secreted by a type I-secretion system and that it serves to activate XA21-mediated immunity. This report has recently been retracted. Here we present data that corrects our previous model. We first show that Ax21 secretion does not depend on the predicted type I secretion systemand that it is processed by the general secretion (Sec) system. We further show that Ax21 is an outer membrane protein, secreted in association with outer membrane vesicles. Finally, we provide data showing that ax21 knockout strains do not overcome XA21-mediated immunity.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020] ; Sciences du monde végétal [076]
Localisation
Fonds IRD [F B010064619]
Identifiant IRD
fdi:010064619
Contact