Carolan Kévin, Ebong S. M. A., Garchitorena Andrès, Landier J., Sanhueza D., Texier G., Marsollier L., Le Gall Philippe, Guégan Jean-François, Lo Seen D. (2014). Ecological niche modelling of Hemipteran insects in Cameroon ; the paradox of a vector-borne transmission for Mycobacterium ulcerans, the causative agent of Buruli ulcer. International Journal of Health Geographics, 13, art. 44 [11 p.]. ISSN 1476-072X.
Titre du document
Ecological niche modelling of Hemipteran insects in Cameroon ; the paradox of a vector-borne transmission for Mycobacterium ulcerans, the causative agent of Buruli ulcer
Année de publication
2014
Auteurs
Carolan Kévin, Ebong S. M. A., Garchitorena Andrès, Landier J., Sanhueza D., Texier G., Marsollier L., Le Gall Philippe, Guégan Jean-François, Lo Seen D.
Source
International Journal of Health Geographics, 2014,
13, art. 44 [11 p.] ISSN 1476-072X
Background: The mode of transmission of the emerging neglected disease Buruli ulcer is unknown. Several potential transmission pathways have been proposed, such as amoebae, or transmission through food webs. Several lines of evidence have suggested that biting aquatic insects, Naucoridae and Belostomatidae, may act as vectors, however this proposal remains controversial. Materials and methods: Herein, based on sampling in Cameroon, we construct an ecological niche model of these insects to describe their spatial distribution. We predict their distribution across West Africa, describe important environmental drivers of their abundance, and examine the correlation between their abundance and Buruli ulcer prevalence in the context of the Bradford-Hill guidelines. Results: We find a significant positive correlation between the abundance of the insects and the prevalence of Buruli ulcer. This correlation changes in space and time, it is significant in one Camerounese study region in (Akonolinga) and not other (Bankim). We discuss notable environmental differences between these regions. Conclusion: We interpret the presence of, and change in, this correlation as evidence (though not proof) that these insects may be locally important in the environmental persistence, or transmission, of Mycobacterium. ulcerans. This is consistent with the idea of M. ulcerans as a pathogen transmitted by multiple modes of infection, the importance of any one pathway changing from region to region, depending on the local environmental conditions.
Plan de classement
Sciences du milieu [021]
;
Entomologie médicale / Parasitologie / Virologie [052]
;
Etudes, transformation, conservation du milieu naturel [082]
Description Géographique
CAMEROUN
Localisation
Fonds IRD [F B010063099]
Identifiant IRD
fdi:010063099
