Publications des scientifiques de l'IRD

Bousema T., Churcher T. S., Morlais Isabelle, Dinglasan R. R. (2013). Can field-based mosquito feeding assays be used for evaluating transmission-blocking interventions ?. Trends in Parasitology, 29 (2), p. 53-59. ISSN 1471-4922.

Titre du document
Can field-based mosquito feeding assays be used for evaluating transmission-blocking interventions ?
Année de publication
2013
Type de document
Article référencé dans le Web of Science WOS:000315180200001
Auteurs
Bousema T., Churcher T. S., Morlais Isabelle, Dinglasan R. R.
Source
Trends in Parasitology, 2013, 29 (2), p. 53-59 ISSN 1471-4922
A recent meta-analysis of mosquito feeding assays to determine the Plasmodium falciparum transmission potential of naturally infected gametocyte carriers highlighted considerable variation in transmission efficiency between assay methodologies and between laboratories. This begs the question as to whether mosquito feeding assays should be used for the evaluation of transmission-reducing interventions in the field and whether these field-based mosquito assays are currently standardized sufficiently to enable accurate evaluations. Here, we address biological and methodological reasons for the observed variations, discuss whether these preclude the use of field-based mosquito feeding assays in field evaluations of transmission-blocking interventions, and propose how we can maximize the precision of estimates. Altogether, we underscore the significant advantages of field-based mosquito feeding assays in basic malaria research and field trials.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052]
Identifiant IRD
fdi:010059003
Contact
  • Coordonnées :
    IST / IRD Ile-de-France
    32 avenue Henri Varagnat
    93140 Bondy Cedex
    France
    Horizon Pleins textes
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