Ahuka-Mundeke S., Mbala-Kingebeni P., Liégeois Florian, Ayouba Ahidjo, Lunguya-Metila O., Demba D., Bilulu G., Mbenzo-Abokome V., Inogwabini B. I., Muyembe-Tamfum J. J., Delaporte Eric, Peeters Martine. (2012). Identification and molecular characterization of new simian T cell lymphotropic viruses in nonhuman primates bushmeat from the Democratic Republic of Congo. Aids Research and Human Retroviruses, 28 (6), p. 628-635. ISSN 0889-2229.
Titre du document
Identification and molecular characterization of new simian T cell lymphotropic viruses in nonhuman primates bushmeat from the Democratic Republic of Congo
Année de publication
2012
Auteurs
Ahuka-Mundeke S., Mbala-Kingebeni P., Liégeois Florian, Ayouba Ahidjo, Lunguya-Metila O., Demba D., Bilulu G., Mbenzo-Abokome V., Inogwabini B. I., Muyembe-Tamfum J. J., Delaporte Eric, Peeters Martine
Source
Aids Research and Human Retroviruses, 2012,
28 (6), p. 628-635 ISSN 0889-2229
Four types of human T cell lymphotropic viruses (HTLV) have been described (HTLV-1 to HTLV-4) with three of them having closely related simian virus analogues named STLV-1, -2, and -3. To assess the risk of cross-species transmissions of STLVs from nonhuman primates to humans in the Democratic Republic of Congo, a total of 330 samples, derived from primate bushmeat, were collected at remote forest sites where people rely on bushmeat for subsistence. STLV prevalences and genetic diversity were estimated by PCR and sequence analysis of tax-rex and LTR fragments. Overall, 7.9% of nonhuman primate bushmeat is infected with STLVs. We documented new STLV-1 and STLV-3 variants in six out of the seven species tested and showed for the first time STLV infection in C. mona wolfi, C. ascanius whitesidei, L. aterrimus aterrimus, C. angolensis, and P. tholloni. Our results provide increasing evidence that the diversity and geographic distribution of PTLVs are much greater than previously thought.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052]
;
Sciences du monde animal [080]
Localisation
Fonds IRD [F B010055948]
Identifiant IRD
fdi:010055948
