Basset C., Rodrigues A.M.S., Eparvier V., Silva M.R.R., Lopes N.P., Sabatier Daniel, Fonty E., Espindola L.S., Stien D. (2012). Secondary metabolites from Spirotropis longifolia (DC) Baill and their antifungal activity against human pathogenic fungi. Phytochemistry, 74, p. 166-172. ISSN 0031-9422.
Auteurs
Basset C., Rodrigues A.M.S., Eparvier V., Silva M.R.R., Lopes N.P., Sabatier Daniel, Fonty E., Espindola L.S., Stien D.
Source
Phytochemistry, 2012,
74, p. 166-172 ISSN 0031-9422
A phytochemical study of the ethyl acetate extract of the roots and adventitious roots of Spirotropis longifolia, a monodominant tree species of the Guianan rainforest, has allowed the isolation of three compounds: 2- hydroxy-8,9-methylenedioxy-2',2'-dimethylpyrano-[5',6':4,3]-6a-prenyl-[6 aS,11aS]-pterocarpan (spirotropin A), 2-hydroxy-8,9-methylenedioxy-2',2'-dimethy1-3',4'-dihydropyrano-[5',6':4 ,3]-6a-prenyl-(6aS,11aS]-pterocarpan (spirotropin B), and 5,7-dihydroxy-6.8-dipreny1-2 '.2 '-dimethylpyrano[5 ',6 ': 3',4]-isoflavone (spirotropone). In addition, 10 known compounds, trans-oxyresveratrol, trans-resveratrol, piceatannol, daidzein, genistein, isoprunetin, lupeol, latifolol, gnetin D and gnetin E, were also isolated. These compounds were evaluated for their antifungal activity and their cytotoxicity, and their structures were established by 1D and 2D NMR, HRMS, CD and optical rotation measurements.
