Grard G., Drexler J. F., Lekana-Douki S., Caron M., Lukashev A., Nkoghe D., Gonzalez Jean-Paul, Drosten C., Leroy Eric. (2010). Type 1 wild poliovirus and putative enterovirus 109 in an outbreak of acute flaccid paralysis in Congo, October-November 2010. Eurosurveillance, 15 (47), p. 6-8. ISSN 1560-7917.
Titre du document
Type 1 wild poliovirus and putative enterovirus 109 in an outbreak of acute flaccid paralysis in Congo, October-November 2010
Grard G., Drexler J. F., Lekana-Douki S., Caron M., Lukashev A., Nkoghe D., Gonzalez Jean-Paul, Drosten C., Leroy Eric
Source
Eurosurveillance, 2010,
15 (47), p. 6-8 ISSN 1560-7917
An outbreak of flaccid paralysis syndrome in adults is ongoing in Congo. Molecular analysis of faecal, throat and cerebrospinal samples identified wildtype 1 poliovirus and an additional enterovirus C strain related to enterovirus 109 as the cause. As of 22 November, the cumulative number of cases was 409, of which 169 (41.3%) were fatal. This is one of the largest wild type 1 poliovirus outbreaks ever described associated with an unusually high case fatality rate.